|
Supreme TWICE-A-DAY
The Most Nutritionally Complete Tablet Available
Indication Take two tablets daily, with a meal or as directed by a health care professional. Description Supreme TWICE-A-DAY is an advanced, scientifically balanced formula provided in a natural base of lecithin and citrus bioflavonoid complex. These 'superfoods' provide functional support to the formula, with lecithin providing a rich source of important phospholipids and citrus bioflavonoid complex providing powerful anti-oxidant support. The tablets are time release to provide a steady supply of nutrients over a six to eight hour period. The advanced technology time release process allows for the gradual erosion of the tablet in the stomach, metering out the nutrients in a controlled manner. This time release technology reduces nutrient waste that occurs when larger doses are taken at one time in a non time release formula. LECITHIN Supreme TWICE-A-DAY incorporates a special Lecithin, a phospholipid composed of glycerol, two fatty acids and a phosphatidic acid. The primary phosphatides are phosphatidyl inositol (PI), phosphatidyl ethanolamine (PE) and phosphatidyl choline (PC). Lecithin is the dietary precursor of acetylcholine, a neurotransmitter required for normal brain function. PC functions structurally as a component of the cell membrane. PC also occurs in plasma lipo-protein complexes where it assists in the transport of lipids throughout the bloodstream. In the bile, PC acts as an emulsifier while aiding in fat transport from the gastrointestinal tract Supreme TWICE-A-DAY contains a special oil free powdered lecithin from non-GMO soybeans containing 97% phosphatides. Each tablet contains 100 mg of lecithin which yields 23 mg of phosphatidyl choline, a powerful fat emulsifying compound that is present in every cell in the body. PC solubilizes fats and cholesterol in the blood stream, solubilizes dietary fats in the intestinal mucosa and maintains structural integrity of cell membranes. PC is a source of choline, a B-complex factor with powerful lipotropic activity that plays a vital role in brain neurotransmission. Lecithin also provides linoleic acid, an omega 6 essential fatty acid which is the precursor to the series l Prostaglandins, hormone like substances that regulate the synthesis of cyclic AMP (adenosine 3',5'-cyclic monophosphate), which in turn regulates hormone, protein, bone, fatty acid, amino acid, glycogen, nerve and energy metabolism. Physical activity plays a central role in the control of lipid metabolism. Increased physical activity induces a number of positive changes in the metabolism of lipoproteins: serum triglycerides are lowered by the increased lipolytic activity and the production of native high-density lipoprotein (HDL) particles is increased. With increased lecithin, cholesterol acyltransferase activity leads to increased production of HDL2, which is catabolised more slowly due to a decreased activity of hepatic lipase. These three effects explain the increased HDL levels of endurance-trained individuals. CITRUS BIOFLAVONOID COMPLEX Bioflavonoids, often called vitamin P (P for permeability), were first discovered and named by Dr. Albert Szent-Gyorgyi, the discoverer of vitamin C. Bioflavonoids are water-soluble flavone derivatives which include Hesperidin, Quercitin, Naringin and Rutin. Bioflavonoids are found along with vitamin C in foods such as citrus fruits, green peppers and buckwheat. Bioflavonoids are essential for the absorption and utilization of vitamin C. The bioavailability of vitamin C is enhanced when adequate bioflavonoids are present, and in turn, the bioavailability of bioflavonoids is enhanced when adequate vitamin C is present. Ideally, bioflavonoids should be in equal ratio with vitamin C as in the Supreme TWICE-A-DAY. They assist vitamin C in keeping collagen, the "intercellular cement" in a healthy condition. As a potent antioxidant, bioflavonoids keep vitamin C and adrenalin from being oxidized by copper-containing enzymes. They reduce the risk of heart disease by their ability to lower cholesterol and triglycerides. They improve capillary permeability and reduce red blood cell aggregation. They have anti-allergy and anti-inflammatory activity and reduce swelling and body fluid concentration at sites of inflammation, and they dilate small arteries, improving circulation. They stimulate bile production, influence endocrine glands, and have anti-parasitic and anti-bacterial properties. Bioflavonoids reduce platelet adhesiveness and reduce the incidence of heart disease and stroke. Together, vitamin C and bioflavonoids have proven helpful in treating capillary injuries and they help minimize contact sport bruising. They have also proven helpful in the treatment of bleeding gums, eczema and hemorrhaging. Supreme TWICE-A-DAY uses one of the most potent forms of bioflavonoids with a Hesperidin content of more than 35%. VITAMIN LEVELS The RDAs - intakes of minerals and vitamins which prevent deficiency symptoms in healthy, average adults - are inadequate for optimum health, especially during stress, growth, pregnancy, lactation, strenuous and athletic activity, healing from disease and injury, and advancing age. At present, the RDA's represent the nutritional equivalent of the minimum wage. Just like the minimum wage, they offer little hope of significantly improving the quality of your life. On June 19, 2002, the American Medical Association, after decades of anti-vitamin policy, has reversed its position and now recommends that Americans take at least one multivitamin pill each day. While most one-a-day multi-vitamin formulas are not enough to maintain optimum health over one's lifetime, they are better than no supplementation at all, and is a welcome beginning to a new appreciation of the role of nutrients in preventing disease. It is tragic that the Medical profession and the pharmaceutical industry have largely ignored the results of numerous published scientific studies on the role of nutrition in maintaining good health. The quality of life for millions could have been improved and countless lives saved if the AMA had adopted this new position 20 years earlier. Supreme TWICE-A-DAY timed release formula represents a significant improvement in meeting the long term dietary needs necessary to maintain long term health, and is the only "ONE-A-DAY'' tablet that provides ALL the essential nutrients necessary for good health. Vitamins in Supreme TWICE-A-DAY All the vitamins including vitamin K, that have been shown to be essential at dosage levels more consistent with long term health, are included in the formula. The minor vitamins biotin and pantothenic acid, for which no RDA's have yet been established, are also included, as these are also essential for optimal health. In the case of vitamin A, a combination of the vitamin and its precursor beta-carotene is used to insure an adequate level of antioxidant activity without including a level of vitamin A that might exceed accepted levels of safety. Minerals in Supreme TWICE-A-DAY The essential minerals play a very important role in the body. They make it possible for muscles to contract, for the brain and the nervous system to work and to combine with amino acids to produce co-enzymes that control the many living processes such as energy production and growth. In nature, the minerals are rarely found alone, but are bound as inorganic compounds in the earth, or in living organisms, with a variety of natural substances as organic complexes. In Supreme TWICE-A-DAY , the minerals are combined with amino acids by a process known as chelation, which mimics the form in which most minerals are found in food. Amino acid chelated minerals can therefore be more rapidly and efficiently absorbed from the digestive tract into the bloodstream than inorganic forms of minerals. Highly bio-available, amino acid chelated minerals are prepared using advanced technical processes that require scrupulous monitoring of mineral/amino acid ratios, pH, and ingredient concentrations. Exact balancing of materials is necessary to avoid the formation of inorganic salts which can irritate the gastrointestinal tract. Amino acid chelation closely resembles how minerals are found in foods & what occurs in the human digestive tract. Amino acid chelates are absorbed rapidly and efficiently, making them the most bio-available of mineral forms. Enerex's chelated minerals are manufactured by a special technology that uses proteolytic enzymes to digest rice protein and citric acid to ionize the minerals. Rice protein is used as a source of amino acids because it is less allergenic than other commonly used proteins such as wheat, yeast, corn and milk. For a more complete description of mineral chelates, please view the article: Synergistically Balanced Amino Acid Chelated Minerals Calcium and magnesium are provided in the ideal 1:1 ratio. Calcium and magnesium are vital components of bone and tooth metabolism. Both participate in energy production, muscle contraction, nerve function, maintenance of the acid-alkali balance of the body fluids, and nucleic acid metabolism. Several smaller doses of calcium and magnesium over the course of the day are absorbed more effectively than one large dose. For more information view: Calcium to Magnesium Ratio Zinc is essential for many physiological processes, including cellular nucleic acid synthesis, sensory taste and smell, keratin metabolism, sexual and reproductive processes, wound healing, etc. Soil deficiency of zinc is widespread, often resulting in zinc deficiency in non-supplemented diets. Zinc and copper compete for absorption in the digestive tract, and therefore are provided in a carefully balanced ratio. Normally, iron absorption from the gastrointestinal tract is a very inefficient process. Concomitant administration of vitamin C and bioflavonoid complex and certain components of the B-complex, especially folic acid and vitamin B12 greatly increase iron uptake. Vitamin B-complex factors stimulate gastric and duodenal secretions, increasing hydrochloric acid production which solubilizes iron for absorption. Vitamin C keeps iron in its reduced state and binds the mineral for easier absorption. Vitamin C is especially useful for raising iron absorption under conditions of iron deficiency The Supreme TWICE-A-DAY includes copper because the incorporation of iron into the oxygen-carrying red blood cell pigment, hemoglobin, is copper-dependent. Molybdenum is also included because of its involvement both in the transport of iron, and in energy production. Iron in Supreme TWICE-A-DAY Ever since an article published in the JULY 26, 1999 Issue of Archives of Internal Medicine, titled Iron, Atherosclerosis, and Ischemic Heart Disease (1) , suggested that elevated iron levels might be a contributing factor in the development of atherosclerosis and ischemic heart disease, there has been a trend among vitamin manufacturers to bring out iron free formulas, and by so doing, creating in the public mind, as well as in the mind of some health care practitioners, a fear that iron supplementation might be harmful. This is an unfortunate misinterpretation of the report. The report relates to a specific type of iron called heme iron, which is found in red meat. The report refers to a study by Snowdon et al (2) that found a threefold difference in risk of fatal coronary disease in 45 to 64 year-old men who ate meat daily, compared to those who did not eat meat. Meat consumption was positively associated with fatal ischemic heart disease in both men and women. This was the first study to clearly show a dose-response relationship between meat consumption and ischemic heart disease risk. The report also shows a lack of correlation between non-heme iron intake and coronary heart disease (CHD), and suggests that dietary non-heme iron does not contribute to an increased cardiovascular risk. Non-heme iron is the type of iron used in most dietary supplements including the Supreme TWICE-A-DAY. The report also refers to a follow-up study of 44,933 men (with no previous history of CHD) aged 40 to 75 years by Ascherio et al (3), which showed, after adjustments for established risk factors, that there was no significant association between total iron intake and risk of CHD. CONCLUSIONS: These results do not support the hypothesis that dietary iron in general increases coronary risk in men; they are consistent, however, with an increased risk of myocardial infarction among men with higher intakes of heme iron (meat eaters), which is itself positively associated with iron stores. The report did not take into account other well-known risk factors in the development of CHD such as smoking, drinking, high fat diet, elevated levels of cholesterol and homocysteine, stress, lack of exercise, heredity and long-term sub-optimal intake of nutrients including vitamin E and C. It could be a fatal mistake to suggest, as the report suggests, that abolishing iron fortification of foods and avoiding nutritional supplements that contain iron will reduce the incidence of CHD. This approach can create a false sense of security, especially amongst middle-age men, if they think that they can avoid CHD without addressing all of the other risk factors. The obvious, but omitted, conclusion of the report would be to recommend a reduction in the dietary intake of heme iron by reducing or eliminating the consumption of red meat. This simple solution would also reduce the other risk factors such as saturated fat and cholesterol, to say nothing of reducing the risk of mad cow disease. This is of course, a political recommendation as well as a scientific one. Any suggestion that consumption of red meat would have a bearing on the development of CHD, or any other health condition, would bring the wrath of the powerful agriculture lobby, which includes the beef and dairy industries. A study published in October 2002, confirms the lack of correlation between ferritin concentrations and transferrin levels in patients with coronary artery disease. In patients referred for coronary angiography, serum ferritin levels were not associated with an increased extent of coronary atherosclerosis (4). The report also discussed the special iron needs of those involved in physical training such as athletes. Physical training reduces iron stores by creating a negative iron balance as shown in athletes. This gives rise to a condition known as sports anemia, a common condition in many athletes, both male and female. Building muscle mass such as in bodybuilding and weightlifting leads to an increased need of iron for myoglobin. The report suggests that it is the lower iron levels in athletes that is responsible for their lower risk of CHD, but avoids other positive benefits of exercise on the incidence of CHD such as improved aerobic capacity, lower body fat and cholesterol, stronger heart etc. Iron deficiency is the most common nutrient deficiency in the world. Groups likely to suffer from iron deficiency include pregnant and lactating women, menstruating women, vegetarians, children during early and adolescent periods of rapid growth, and those who experience symptoms of fatigue. In fact, the majority of the population suffers from some form of sub-clinical iron deficiency. Iron absorption from red meat (heme iron) is about 15%, whereas absorption from plant sources (non-heme iron) is only about 4%. Iron absorption is governed by the body's need: an iron-anemic person may absorb 50-60% of iron present in food. Inorganic iron such as ferrous sulfate is often used in low quality dietary supplements and in fortification of cereals. Inorganic iron is poorly absorbed and can cause constipation and gastric distress - it should be avoided. In summary, to meet the optimum dietary needs of the majority of the population, organic (non-heme iron) supplementation along with optimum levels of all the other minerals, vitamins and enzymes is essential to maintain good health throughout one's lifetime. Supreme TWICE-A-DAY meets the optimum nutritional needs of the majority of the population.
Silica in Supreme TWICE-A-DAY Supreme TWICE-A-DAY contains bamboo extract, the richest known source of natural silica containing over 70% organic silica. This is more than 30 times the level as found in the widely used Horsetail plant (Equisetum), which contains about 2-3% silica. The bamboo extract is prepared from Tabashir bamboo stem from India (Bambusa vulgaris). Silicon (Si) is the second most abundant element on earth after oxygen. It is a sister element of carbon. Silicon's role as an essential nutrient in human nutrition was not established until 1972, but silicon is now known to play a part in the integrity of the skin, ligaments, tendons, bone and in the health of the arteries. The body constantly metabolizes silicic acid. Silica is eliminated through such natural processes as urination, hair loss and nail trimming. This natural secretion of silica can be from 10 to 40 mg daily. The average adult body contains about 20 grams of silica, and it is necessary for the body's silica stores to be maintained at this level to promote good health. As we age, less silica is assimilated; therefore daily supplementation with Supreme TWICE-A-DAY will help maintain this necessary equilibrium and to minimize the effects of premature ageing. Silicon is thought to improve the cardiovascular system, as it is essential to the structural integrity, elasticity and permeability of the arteries. Silica may be useful in reducing blood fats & cholesterol. Arthrosclerosis can occur as a result of silicon deficiency whereas silicon is abundant (up to 14 times more) in the arteries of people who are free of heart disease. Silicon improves the condition of the hair, nails, teeth, gums and skin and has been used to alleviate eczema and psoriasis. Silica plays an essential role in mineral absorption and may help in re-calcifying de-calcified bones & de-calcifying soft tissue deposits of calcium. Silicon enhances the function of iron, calcium, magnesium, potassium and boron, and is essential for normal bone development which may help prevent osteoporosis. Silicon helps maintain the correct calcium-magnesium balance. Silicon may be useful in strengthening the musculo-skeletal system, preventing injuries and helping bones to heal in athletes & others. Silicon supplementation may retard the ageing process. At birth, the body contains a maximum level of silica that declines with age. As the body's natural level of silica declines, it exhibits the signs attributable to ageing such as bone loss, dry and wrinkled skin, weakened teeth and gums and hair loss. Silicon converts aluminum from both water and other dietary sources into insoluble hydroxy-aluminosilicates, which cannot enter the bloodstream or brain. This has important consequences for preventing the development of Alzheimer's dementia by assisting the body in eliminating aluminum. Aluminum is thought to be a causative factor in the development of Alzheimer's disease. Silicon stimulates chondroblasts to deposit chondroitin sulfate and hyaluronic acid into the cartilage matrix. This has important implications in managing arthritis pain, as silicon will improve the function and effectiveness of glucosamine sulfate which is the precursor of both chondroitin sulfate and hyaluronic acid. Silicon may help protect against and heal gastric ulcers and arthritis (connective tissue healing). FUNCTIONS OF SILICON
The inclusion of silica makes Supreme TWICE-A-DAY the most complete TWICE a day formula available. Supreme TWICE-A-DAY contains optimum levels of important essential trace minerals. Selenium (Se) and other antioxidant nutrients are powerful anti-ageing factors that protect cells from oxidative and free radical damage that hastens cell death. By preventing and detoxifying free radicals and peroxides, Se protects cells from the relentless destructive effects of these substances. Se is particularly important as a component of glutathione peroxidase, a protective antioxidant enzyme broadly distributed throughout the body. This enzyme plays a key role in protecting cell membrane lipids from random oxidation. Se is also important in nucleic acid metabolism, immune system physiology and reproductive processes. Research on the bio-geographical distribution of Se conclusively indicates that higher incidence's of cancers occur where soil Se levels, and thus food Se levels, are low. Vanadium (Vn) plays an essential role in growth, iron & lipid metabolism, reproduction & bone development and may replace phosphorous in tooth enamel thereby retarding tooth decay. Vn stimulates oxidation of glucose to energy in fat cells by mimicking the action of insulin, and stimulates glycogen formation in the liver & diaphragm. Molybdenum (Mo) is a co-factor in the enzyme xanthine oxidase. Mo is involved in mobilizing iron from liver storage to oxidize aldehydes. Mo helps to remove nitrogen waste from the body through the formation of uric acid (purine metabolism). Uric acid is a powerful anti-oxidant. Mo appears to play a role in the control of ageing. Mo is involved in fat metabolism & energy production through the Mo activated enzyme (aldehyde oxidase). Mo may play a role in preventing tooth decay by promoting the retention of fluoride. Chromium (Cr) is a component of glucose tolerance factor. Cr is involved in glucose metabolism that is necessary for energy production. Cr binds insulin to cells potentiating its action in allowing cells to take in glucose. Cr indirectly affects blood fat levels and stabilizes blood sugar levels. Cr is involved in protein synthesis and increases lean muscle mass. Cr stimulates liver enzymes involved in synthesis of cholesterol & fatty acids, and lowers cholesterol & increases beneficial HDL. Boron (B) may retard bone loss. Since osteoporosis is reaching epidemic proportions in larger numbers of the population, especially in those over 50 years of age, this is important news. Osteoporosis occurs when the osteoblasts cannot replace lost bone tissue as fast as the osteoclasts break it down. Osteoclasts deplete bone at a faster rate after menopause, leaving women at a greater risk of bone degradation. B appears to have a moderating effect on this process. Enzymes in Supreme TWICE-A-DAY Minerals and vitamins are the partners of enzymes - co-enzymes - necessary for enzymes to carry out their specific and vitally important functions. Minerals carry electric signals, the messages of life. Vitamins activate enzymes. Each must have the other - like a biochemical marriage. Without minerals and vitamins, enzymes could not carry out their work, and we could not live. With the help of minerals as well as vitamin co-enzymes, digestive enzymes regulate how foods (macronutrients) become micronutrients that living tissues can use. Minerals and vitamin-activated enzymes also determine which substances are drawn through membranes into cells to take part in the cells' molecular "dance of life". If vitamins and minerals are lacking, enzymes don't function, and the processes on which life depends must slow down or stop. Supreme TWICE-A-DAY Contains Several Digestive Enzymes:
The body's supply of enzymes, vitamins (co-enzymes) and minerals depends largely on the diet. Health can be compromised if there is insufficient supply of any of these nutrients. To help meet the nutrient requirements for optimum health, Supreme TWICE-A-DAY is fortified with lecithin and citrus bioflavonoids, along with optimum amounts of all essential vitamins, the complete range of amino acid chelated macro and trace minerals, plus enzymes, to provide the most advanced one-a-day dietary supplement in the world. Making of Supreme TWICE-A-DAY After careful consideration of all the factors, Supreme TWICE-A-DAY is presented in tablet form rather than in gelatin capsules. Tablets can be made more stable and are not affected by high temperatures and humidity, which can cause gelatin capsules to soften and leak. Also, gelatin capsules have a higher moisture content that can adversely affect the stability of the formula. Some methods of manufacturing tablets can cause the temperature of the ingredients to rise to a level that can destroy the enzymes and some of the vitamins. All of the advanced research that has gone into producing Supreme TWICE-A-DAY would be wasted if the sensitive ingredients were destroyed during the manufacturing process. To insure that the nutrients in Supreme TWICE-A-DAY are presented in the best possible way, with maximum protection of the heat sensitive ingredients, the timed release tablets are made using a unique, state-of-the-art process known as high-density Chilsonation. An advanced device - a Chilsonator - represents the first step in the processing of many raw materials. The Chilsonator houses grooved, counter-rotating rollers pressed tightly against one another by hydraulic pressure. Raw materials are placed into the hopper of the Chilsonator and are fed by a system of horizontal and vertical screws into these rollers. As the materials pass through the grooves in the rollers, the materials are compacted under high pressure and emerge from the Chilsonator as dense pellets. The pellets are milled into a granular powder using a Fitz Mill, and then passed through a series of vibrating screens to produce a uniform, free flowing granulation. The Chilsonation process results in a finished powder that is 3 to 4 times denser than the starting material. The Chilsonator allows the production of smaller tablets without a reduction in potency, resulting in a tablet that is easer to swallow and therefore more desirable to consumers. The Chilsonator alters the flow characteristics of raw materials, making them easier to use in making tablets, resulting in better dispersion of the nutrients in the body. This is extremely important, because uniform dispersion of nutrients enhances nutrient bioavailability. The ability to alter flow characteristics makes the Chilsonator ideal for use in dry granulation of raw materials. Wet granulation, the traditional industry standard for preparing materials for tablets and capsules, requires the use of alcohol solvents and high temperature drying to achieve the necessary material characteristics. Chilsonation completely eliminates the need for this destructive process. Without further protection, some of the nutrients could be damaged by exposure to the atmosphere. This can reduce their activity and allow oxidation, which may cause some of the ingredients to be chemically altered to produce undesirable breakdown products such as free radicals. After Chilsonation, the tablets are coated with an advanced protective layer. This coating, known as LustreClear, is made from a special vegetable cellulose complex and purified water. No organic solvents are used at all. Thus, the coating is hypoallergenic and free from chemicals or sugar that can cause allergies in sensitive people. In addition to its protective action, the LustreClear coating gives the tablets an even smoother finish, making them easier to swallow than conventional tablets or capsules. Finally, Supreme TWICE-A-DAY tablets are packaged in PETE bottles. PETE provides a superior moisture and oxygen barrier compared to the more common HDPE plastic that most vitamin manufactures use. To add a further degree of protection every bottle of Supreme TWICE-A-DAY contains a small package of silica gel desiccant. The silica gel desiccant absorbs any moisture that may enter the bottle during manufacturing and prevents deterioration of the tablets. Taking of Supreme TWICE-A-DAY With Supreme TWICE-A-DAY, the nutrients are incorporated into a single timed release tablet to ensure optimal absorption and a beneficial effect over the whole day. Taking one Supreme TWICE-A-DAY tablet with a meal provides sufficient levels of the essential vitamins, minerals and enzymes necessary to help ensure a nutritionally balanced meal. It is also recommended to include a dietary supplement of omega 3 and omega 6 essential fatty acids (EFA'S) as these are often deficient in the average diet as well. The OMEGA 3-6+9 capsules from Enerex provide the ultimate in EFA supplementation. Packaging: Packed in recyclable amber PETE (Bisphenol A free) containers to provide the best protection for the product against oxidation. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
